Romelu Lukaku, Giacomo Raspadori and Scott McTominay attempt to give Napoli a Scudetto increase, however Venezia are making themselves powerful to beat.
It kicks off at 11.30 GMT.
Atalanta and Inter go head-to-head this night, so with solely three factors separating these sides, Napoli are hoping to take benefit by leaping to high spot.
The one remaining is David Neres, as Andre Frank Zambo Anguissa and David Neres are again on the bench after harm.
Meaning Billy Gilmour is once more partnering McTominay in midfield, with Lukaku and Raspadori forming a powerful bond upfront.
Venezia stay within the hazard zone, however have turned a nook just lately and made themselves very powerful to beat, incomes three consecutive attracts in opposition to Lazio, Atalanta and Como.
John Yeboah is suspended, with Marin Sverko, Filip Stankovic and Michael Svoboda injured.
Gaetano Oristanio has additionally been scuffling with flu signs over the previous few days.
This is a crucial event for Alessio Zerbin, who joined Venezia from Napoli on mortgage in January, with an choice to purchase that turns into an obligation in the event that they keep away from relegation for €4m.
Venezia vs. Napoli line-ups
Venezia (3-5-2): Radu; Schingtienne, Idzes, Cande; Zerbin, Perez, Nocolussi Caviglia, Duncan, Ellertsson; Fila, Maric.
Napoli (4-3-3): Meret; Di Lorenzo, Rrahmani, Buongiorno; Politano, Gilmour, Lobotka, McTominay, Spinazzola; Lukaku, Raspadori
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