Scott McTominay is anticipated to begin in central midfield for Napoli regardless of with Antonio Conte confirming a 3-5-2 line-up towards Fiorentina.
It kicks off at 15:00 CET (14:000 GMT) on the Stadio Maradona.
The Partenopei want a win to maintain tempo with Inter who beat strugglers Monza 3-2 at San Siro final evening.
David Neres, Pasquale Mazzocchi and Frank Anguissa, so Conte is anticipated to substantiate the identical workforce that collected a 1-1 draw towards Inter final week with Romelu Lukaku and Giacomo Raspadori in assault.
Fiorentina should cope with out Edoardo Bove, Andrea Colpani and Michael Folorunsho, whereas Rolando Mandragora and Nicolò Zaniolo are suspended.
The Tuscans will barely rotate as they’ve a key Convention League recreation towards Panathinaikos subsequent week.
The Viola misplaced 3-2 in Greece within the Spherical of 16 first leg final week.
Moise Kean will begin up entrance alongside Lucas Beltran, whereas David de Gea will return between the sticks after resting within the newest European fixture.
Napoli vs Fiorentina – the place to observe on TV
The sport will probably be obtainable to stream reside on OneFootball within the UK. FOX Deportes will broadcast the sport reside in USA, whereas Paramount+ and FuboTV will present it reside in streaming.
Napoli vs Fiorentina – possible line-ups
Napoli (3-5-2): Meret; Di Lorenzo, Rrahmani, Buongiorno; Politano, Gilmour, Lobotka, McTominay, Spinazzola; Lukaku, Raspadori.
Fiorentina (3-5-2): De Gea; Comuzzo, Marí, Ranieri; Dodô, Fagioli, Cataldi, Ndour, Gosens; Beltran, Kean.